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Tên sản phẩm : Omlek 20
Composition Each tablet contains: OmeprazoleB.P20mg
Pharmacodynamic /pharmacologicalproperties Omprazol is a compound anti-details, no antibacterial effect parasympathetic of antagonists to histamine H2, but are effective in preventing gastric acid secretion by inhibiting the specific system ezym H + / K + ATPase in the details ofgastric parietal cells. Because this system is seen as the acid pumps in the stomach lining. Effects are dose related and leads to inhibition of both basic acid secretion stimulated acid secretion regardless of the stimuli. In animals, after the rapid clearance from the plasma, omeprazole can be found in the mucous membrane of the stomach after 1 day or more.
Anti-weather activity: The activity of acid-resistance occurs after dose Omeprazole for about 1 hour, and reached a maximum of about 2 hours. Inhibition of acid secretion is about 50% of maximum in 24 hours and lasts no more than 72 hours. Inhibit acid secretion of omeprazole increased after 4 days with a constant daily dose. In some patients, the dose of oral omeprazole on 1 times from 10mg to 40mg produced 100% inhibition of gastric acid for 24 hours.
Pharmacokinetics Omeprazole is formulated in the form of particles dissolve in the intestine and is absorbed there. Rapidly absorbed with peak plasma concentrations are reached within 0.5 to 3.5 hours. Most of the drug is eliminated via urine under sub metabolism. In patients with chronic renal clearance delay dependent decrease in creatinine clearance.
specify -          - Prophylaxis of recurrent gastro-duodenal ulcers, reflux esophagitis.
- In combination with antibiotic treatment of duodenal ulcer to Helicobacer pylori
- Treatment of heartburn in esophageal reflux disease
- Zollinger-Ellison syndrome
Contraindications Hypersensitivity to anycomponentofthedrug
Dosage /use -          Peptic ulcer, reflux oesophagitis: 20 mg per day, for 4 to 8 weeks of treatment.
- Zollinger-Ellison syndrome: the recommended starting dose is 60 mg 1 time per day. Should adjust the dose and duration of treatment for each patient.
- No need to adjust in elderly patients, renal or hepatic dysfunction. Omlek should be swallowed whole without chewing or breaking. Drug before meals.
Do not wanttoeffect/side effects Omlek generally well tolerated. Common symptoms such as headache, diarrhea, constipation, flatulence, rash ... can be transient and mild
Women whoarepregnant/lactating It should not be used during pregnancy and breastfeeding unless absolutely necessary. Safety and effectiveness in children have not been determined.
Packing Blister of 10capsules, boxof 10blisters
Preservation Dry place, below 30C, protected from light, out of reach of children.
Marketing anddistribution INFO PHARMA
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