|
Composition |
Each capsule contains
Clotrimazole 100mg and Metronidazole 500mg.
There are also Polyethylene glycol E-3350 powder, Polydthylene glycol 400, Glycerin, Glycerin of saturated fatty acids, iron oxide black IC 77 499, 7749I IC red iron oxide, titanium dioxide, 77,891, Purified Water.
|
|
Specify |
Clotrimazole isanimidazolederivativewitha broad spectrumanti-fungal activity. Thisantifungaleffectbyinhibitingthesynthesisofergosterol, theprocessofthisinhibitionleadstodamageofthestructureand function of thefungalcell membrane.
Clotrimazole hasbroadspectrumanti-fungal activityin vitroandin vivo, includingCandiaalbicans, skinfungus, yeast, mold....
In addition to itsanti-fungal, clotrimazolealsoassistanttoTrichomonasvaginalis, gram-duong.No doesnotinfluencelacobacilli.
Metronidazole isanantibacterialagentbelongingtothenitro-5-imidazole. Itaffectsawiderangeofpathogenic bacteria, especially Bacteroidesspecies, clostridia, eubacteria, Fusobacteria, Gardnerellavaginalis, andanaerobic bacteria, Banlantidiumcoli.
Metronidazole enterstarget cellsin bacteriaandprotozoacanbeactivatedbypassivediffusionandbyreductionofthenitrogroupbypurivate-ferredoxin oxidoreductase. Thereby creatingunstableintermediatesinteractwithDNAto causedamagetotheDNAstructuretwistedandbrokenleading toinhibitionofproteinsynthesisandcelldestructionintheaffectedcreatures. |
|
Pharmacokinetics |
After vaginal, lessdrugabsorption, mainlyworkonsite. The drug isexcretedinthemechanismofvaginalself-cleaning filter |
|
Use |
Vag-Linazol isusedin the treatment ofmixedvaginitiscaused byCandidaalbicansyeastinfections, Trichomanosvaginalis, Gardnerellavaginalisandanaerobicbacteriacommonlyfoundinthevagina. |
|
Contraindications |
Hypersensitivity toanycomponentofthedrughistoryofhematopoieticspeakers, centralnervoussystemdisease inthefirstthreemonthsofpregnancy. |
|
Dosage /use |
Placed in thevagina1tabletatbedtimefor10nightsorduringspecifiedby a physician. |
|
Do not want to effect/side effects |
Rarely patientsmay experiencea burning sensationormild irritationatthesitewhenusing this medicine. Veryrarelypatientsfindthistooannoyingirritationand must betreated. |
|
Women whoarepregnant/lactating |
Pregnant women: Metronidazole is not recommended for use in the first 3 months of pregnancy. Although animal studies does not indicate direct harmful effects with pregnancy, the development of the embryo / fetus or infant development in animals at birth
Women breastfeeding Metronidazole can go into the milk should stop breastfeeding while taking the drug.
|
|
Packing |
Box of 2 blisters x5 soft capsulesvaginally |
|
Preservation |
Keep ina cool dryplaceatatemperatureof30C |
|
Marketing anddistribution |
INFO PHARMA |
